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Gene Information
Gene ID:12298
Symbol:Cacnb4
Full Name:calcium channel, voltage-dependent, beta 4 subunit
Alias:3110038O15Rik|Cchb4|MGC31529|lethargic|lh
Organism:Mus musculus (Mouse)
Chromosome:2
Genetic Location:2 C1.1|2 31.5 cM
Physical Location:52283839-52532100 on NC_000068.6, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 785    Symbol (Name): CACNB4 (calcium channel, voltage-dependent, beta 4 subunit)
Ortholog Status:The human GeneID 785 is not in current human dataset.
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcp1Alcohol Preference Drinking22819-35 (cM)5.3 SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001037099.1NP_001032176.1NC_000068.6 range: 52283839..52532100, complement
NM_146123.2NP_666235.1NC_000068.6 range: 52283839..52532100, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005891voltage-gated calcium channel complexCellular ComponentIMP (9705268)
GO:0005891voltage-gated calcium channel complexCellular ComponentIDA (10328888)
GO:0005853eukaryotic translation elongation factor 1 complexCellular ComponentRCA (16141072)
GO:0005624membrane fractionCellular ComponentRCA (16141072)
GO:0008331high voltage-gated calcium channel activityMolecular FunctionTAS (10494839)
GO:0003746translation elongation factor activityMolecular FunctionRCA (16141072)
GO:0005515protein bindingMolecular FunctionIPI (10328888)
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0005216ion channel activityMolecular FunctionIEA
GO:0005244voltage-gated ion channel activityMolecular FunctionIEA
GO:0005245voltage-gated calcium channel activityMolecular FunctionIMP (9705268|12151514)
GO:0005245voltage-gated calcium channel activityMolecular FunctionRCA (16141072)
GO:0005262calcium channel activityMolecular FunctionIEA
GO:0035249synaptic transmission, glutamatergicBiological ProcessIMP (10322048)
GO:0042391regulation of membrane potentialBiological ProcessIMP (12151514|15637280)
GO:0046058cAMP metabolic processBiological ProcessIMP (7595494)
GO:0048536spleen developmentBiological ProcessIMP (5037658)
GO:0048538thymus developmentBiological ProcessIMP (5037658)
GO:0048541Peyer's patch developmentBiological ProcessIMP (5037658)
GO:0048747muscle fiber developmentBiological ProcessIMP (17320843)
GO:0050852T cell receptor signaling pathwayBiological ProcessIMP (15637280|17028169)
GO:0050877neurological system processBiological ProcessIMP (1321503|9293489)
GO:0030217T cell differentiationBiological ProcessIMP (17028169)
GO:0019227action potential propagationBiological ProcessIMP (7261997)
GO:0014051gamma-aminobutyric acid secretionBiological ProcessIMP (7595494)
GO:0006414translational elongationBiological ProcessRCA (16141072)
GO:0006810transportBiological ProcessIEA
GO:0006811ion transportBiological ProcessIEA
GO:0006816calcium ion transportBiological ProcessIMP (7595494|10407181)
GO:0006816calcium ion transportBiological ProcessRCA (16141072)
GO:0006874cellular calcium ion homeostasisBiological ProcessIMP (15637280)
GO:0007214gamma-aminobutyric acid signaling pathwayBiological ProcessIMP (7472490|7562514|8388308)
GO:0007528neuromuscular junction developmentBiological ProcessIMP (17320843)
GO:0007628adult walking behaviorBiological ProcessIMP (7562514|10328888|12223573)
GO:0051932synaptic transmission, GABAergicBiological ProcessIMP (10322048)
Other Database Cross Links
NCBI Entrez Gene:12298
MGI:MGI:103301
Ensembl:ENSMUSG00000017412
dbSNP:Cacnb4
AceView:Cacnb4