ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

14127

Symbol:

Fcer1g

Full Name:

Fc receptor, IgE, high affinity I, gamma polypeptide

Alias:

AI573376|CD23|FcR-gamma|FcR[g]|FcRgamma|Fce1g|Ly-50

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H3|1 93.3 cM

Physical Location:

173159702-173164479 on NC_000067.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 2207 Symbol (Name): FCER1G (Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide)

Ortholog Status:

The human GeneID 2207 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw1	Acute Alcohol Withdrawal	1	96	172.3-176.5 (Mb)	5.6	3.00E-07	Significant	PARC
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010185.4	NP_034315.1	NC_000067.5 range: 173159702..173164479, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0016021	integral to membrane	Cellular Component	IEA
GO:0016020	membrane	Cellular Component	IEA
GO:0005887	integral to plasma membrane	Cellular Component	IDA (2527850)
GO:0009897	external side of plasma membrane	Cellular Component	IDA (2527850\|14764707)
GO:0045121	membrane raft	Cellular Component	TAS (12192036)
GO:0032998	Fc-epsilon receptor I complex	Cellular Component	IMP (14764707)
GO:0019863	IgE binding	Molecular Function	IMP (14764707)
GO:0019863	IgE binding	Molecular Function	IDA (14764707)
GO:0019864	IgG binding	Molecular Function	IMP (14643301)
GO:0019767	IgE receptor activity	Molecular Function	IMP (14764707)
GO:0019767	IgE receptor activity	Molecular Function	IDA (14764707)
GO:0004888	transmembrane receptor activity	Molecular Function	IEA
GO:0019863	IgE binding	Molecular Function	IDA (2527850)
GO:0004872	receptor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (12893283)
GO:0032765	positive regulation of mast cell cytokine production	Biological Process	IMP (14764707)
GO:0050778	positive regulation of immune response	Biological Process	IMP (10395649)
GO:0033026	negative regulation of mast cell apoptosis	Biological Process	IDA (14764707)
GO:0050776	regulation of immune response	Biological Process	IMP (11911824)
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	Biological Process	IMP (11911824)
GO:0050766	positive regulation of phagocytosis	Biological Process	IMP (11237803\|11901193\|11911823)
GO:0043306	positive regulation of mast cell degranulation	Biological Process	IDA (14764707)
GO:0045576	mast cell activation	Biological Process	IMP (14764707)
GO:0045576	mast cell activation	Biological Process	IDA (14764707)
GO:0033026	negative regulation of mast cell apoptosis	Biological Process	IMP (14764707)
GO:0042742	defense response to bacterium	Biological Process	IMP (11237803)
GO:0043306	positive regulation of mast cell degranulation	Biological Process	IMP (14764707)
GO:0032765	positive regulation of mast cell cytokine production	Biological Process	IDA (14764707)
GO:0032760	positive regulation of tumor necrosis factor production	Biological Process	IMP (10229794\|14764707)
GO:0032760	positive regulation of tumor necrosis factor production	Biological Process	IDA (14764707)
GO:0001812	positive regulation of type I hypersensitivity	Biological Process	IMP (14764707)
GO:0002431	Fc receptor mediated stimulatory signaling pathway	Biological Process	IMP (14764707)
GO:0001798	positive regulation of type IIa hypersensitivity	Biological Process	IMP (8976192\|11901193\|11911824)
GO:0006911	phagocytosis, engulfment	Biological Process	IMP (11237803\|11901193\|11911823)
GO:0007165	signal transduction	Biological Process	IDA (12192036)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	IDA (9000133)
GO:0007166	cell surface receptor linked signal transduction	Biological Process	IMP (11911823\|11911824)
GO:0016064	immunoglobulin mediated immune response	Biological Process	IMP (10395649\|14643301)
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological Process	IMP (14643301)
GO:0030593	neutrophil chemotaxis	Biological Process	IMP (8976192\|10229794\|11420040)
GO:0032733	positive regulation of interleukin-10 production	Biological Process	IMP (11911824)
GO:0032755	positive regulation of interleukin-6 production	Biological Process	IDA (14764707)
GO:0032755	positive regulation of interleukin-6 production	Biological Process	IMP (14764707)
GO:0001805	positive regulation of type III hypersensitivity	Biological Process	IMP (8976192)