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Gene Information
Gene ID:14127
Symbol:Fcer1g
Full Name:Fc receptor, IgE, high affinity I, gamma polypeptide
Alias:AI573376|CD23|FcR-gamma|FcR[g]|FcRgamma|Fce1g|Ly-50
Organism:Mus musculus (Mouse)
Chromosome:1
Genetic Location:1 H3|1 93.3 cM
Physical Location:173159702-173164479 on NC_000067.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2207    Symbol (Name): FCER1G (Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide)
Ortholog Status:The human GeneID 2207 is not in current human dataset.
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcw1Acute Alcohol Withdrawal196172.3-176.5 (Mb)5.63.00E-07SignificantPARC
Calw1/Alcdp1Chronic Alcohol Withdrawal19689-106.3 (cM)7.62.00E-09SignificantPARC
Ap1qAlcohol Preference Drinking17645-95 (cM)4.5 SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_010185.4NP_034315.1NC_000067.5 range: 173159702..173164479, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentIEA
GO:0016020membraneCellular ComponentIEA
GO:0005887integral to plasma membraneCellular ComponentIDA (2527850)
GO:0009897external side of plasma membraneCellular ComponentIDA (2527850|14764707)
GO:0045121membrane raftCellular ComponentTAS (12192036)
GO:0032998Fc-epsilon receptor I complexCellular ComponentIMP (14764707)
GO:0019863IgE bindingMolecular FunctionIMP (14764707)
GO:0019863IgE bindingMolecular FunctionIDA (14764707)
GO:0019864IgG bindingMolecular FunctionIMP (14643301)
GO:0019767IgE receptor activityMolecular FunctionIMP (14764707)
GO:0019767IgE receptor activityMolecular FunctionIDA (14764707)
GO:0004888transmembrane receptor activityMolecular FunctionIEA
GO:0019863IgE bindingMolecular FunctionIDA (2527850)
GO:0004872receptor activityMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIPI (12893283)
GO:0032765positive regulation of mast cell cytokine productionBiological ProcessIMP (14764707)
GO:0050778positive regulation of immune responseBiological ProcessIMP (10395649)
GO:0033026negative regulation of mast cell apoptosisBiological ProcessIDA (14764707)
GO:0050776regulation of immune responseBiological ProcessIMP (11911824)
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class IBiological ProcessIMP (11911824)
GO:0050766positive regulation of phagocytosisBiological ProcessIMP (11237803|11901193|11911823)
GO:0043306positive regulation of mast cell degranulationBiological ProcessIDA (14764707)
GO:0045576mast cell activationBiological ProcessIMP (14764707)
GO:0045576mast cell activationBiological ProcessIDA (14764707)
GO:0033026negative regulation of mast cell apoptosisBiological ProcessIMP (14764707)
GO:0042742defense response to bacteriumBiological ProcessIMP (11237803)
GO:0043306positive regulation of mast cell degranulationBiological ProcessIMP (14764707)
GO:0032765positive regulation of mast cell cytokine productionBiological ProcessIDA (14764707)
GO:0032760positive regulation of tumor necrosis factor productionBiological ProcessIMP (10229794|14764707)
GO:0032760positive regulation of tumor necrosis factor productionBiological ProcessIDA (14764707)
GO:0001812positive regulation of type I hypersensitivityBiological ProcessIMP (14764707)
GO:0002431Fc receptor mediated stimulatory signaling pathwayBiological ProcessIMP (14764707)
GO:0001798positive regulation of type IIa hypersensitivityBiological ProcessIMP (8976192|11901193|11911824)
GO:0006911phagocytosis, engulfmentBiological ProcessIMP (11237803|11901193|11911823)
GO:0007165signal transductionBiological ProcessIDA (12192036)
GO:0007166cell surface receptor linked signal transductionBiological ProcessIDA (9000133)
GO:0007166cell surface receptor linked signal transductionBiological ProcessIMP (11911823|11911824)
GO:0016064immunoglobulin mediated immune responseBiological ProcessIMP (10395649|14643301)
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class IIBiological ProcessIMP (14643301)
GO:0030593neutrophil chemotaxisBiological ProcessIMP (8976192|10229794|11420040)
GO:0032733positive regulation of interleukin-10 productionBiological ProcessIMP (11911824)
GO:0032755positive regulation of interleukin-6 productionBiological ProcessIDA (14764707)
GO:0032755positive regulation of interleukin-6 productionBiological ProcessIMP (14764707)
GO:0001805positive regulation of type III hypersensitivityBiological ProcessIMP (8976192)
Other Database Cross Links
NCBI Entrez Gene:14127
MGI:MGI:95496
Ensembl:ENSMUSG00000058715
dbSNP:Fcer1g
AceView:Fcer1g