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Gene Information
Gene ID:14130
Symbol:Fcgr2b
Full Name:Fc receptor, IgG, low affinity IIb
Alias:AI528646|CD32|F630109E10Rik|Fc[g]RII|FcgRII|Fcgr2|Fcgr2a|Fcr-2|Fcr-3|Ly-17|Ly-m20|LyM-1|Lym-1
Organism:Mus musculus (Mouse)
Chromosome:1
Genetic Location:1 H3|1 92.3 cM
Physical Location:172890688-172906201 on NC_000067.5, complement
Gene Type:protein-coding
Human Ortholog:GeneID: 2213    Symbol (Name): FCGR2B (Fc fragment of IgG, low affinity IIb, receptor (CD32))
Ortholog Status:The human GeneID 2213 is not in current human dataset.
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcw1Acute Alcohol Withdrawal196172.3-176.5 (Mb)5.63.00E-07SignificantPARC
Calw1/Alcdp1Chronic Alcohol Withdrawal19689-106.3 (cM)7.62.00E-09SignificantPARC
Ap1qAlcohol Preference Drinking17645-95 (cM)4.5 SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001077189.1NP_001070657.1NC_000067.5 range: 172890688..172906201, complement
NM_010187.2NP_034317.1NC_000067.5 range: 172890688..172906201, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016021integral to membraneCellular ComponentIDA (8552190)
GO:0016020membraneCellular ComponentIEA
GO:0009897external side of plasma membraneCellular ComponentIDA (8552190|8769481)
GO:0005887integral to plasma membraneCellular ComponentIC (8552190)
GO:0005856cytoskeletonCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005576extracellular regionCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIPI (12893283)
GO:0005057receptor signaling protein activityMolecular FunctionTAS (11994421)
GO:0004872receptor activityMolecular FunctionIEA
GO:0019864IgG bindingMolecular FunctionIDA (9551950)
GO:0050766positive regulation of phagocytosisBiological ProcessIDA (8769481)
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class IIBiological ProcessIMP (14643301)
GO:0030889negative regulation of B cell proliferationBiological ProcessIMP (8552190)
GO:0045576mast cell activationBiological ProcessIDA (8769481)
GO:0001811negative regulation of type I hypersensitivityBiological ProcessIMP (8552190)
GO:0016064immunoglobulin mediated immune responseBiological ProcessIMP (10395649|14643301)
GO:0007166cell surface receptor linked signal transductionBiological ProcessIMP (8552190)
GO:0006955immune responseBiological ProcessIMP (11994421)
GO:0006952defense responseBiological ProcessIMP (11994421)
GO:0006911phagocytosis, engulfmentBiological ProcessIDA (8769481)
GO:0002862negative regulation of inflammatory response to antigenic stimulusBiological ProcessIMP (16492738)
GO:0050777negative regulation of immune responseBiological ProcessIMP (8552190|10395649)
Other Database Cross Links
NCBI Entrez Gene:14130
MGI:MGI:95499
Ensembl:ENSMUSG00000026656
dbSNP:Fcgr2b
AceView:Fcgr2b