ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Full Name:

hemolytic complement

Alias:

C5|C5a|He

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

2 cen-C1|2 23.5 cM

Physical Location:

34838850-34916915 on NC_000068.6, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 727 Symbol (Name): C5 (complement component 5)

Ortholog Status:

The human GeneID 727 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcp1	Alcohol Preference Drinking	2	28	19-35 (cM)	5.3		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_010406.1	NP_034536.1	NC_000068.6 range: 34838850..34916915, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005576	extracellular region	Cellular Component	IEA
GO:0005579	membrane attack complex	Cellular Component	IEA
GO:0005615	extracellular space	Cellular Component	RCA (12466851)
GO:0004866	endopeptidase inhibitor activity	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IEA
GO:0019835	cytolysis	Biological Process	IEA
GO:0006958	complement activation, classical pathway	Biological Process	IEA
GO:0006957	complement activation, alternative pathway	Biological Process	IEA
GO:0006956	complement activation	Biological Process	IEA
GO:0006955	immune response	Biological Process	IEA
GO:0006954	inflammatory response	Biological Process	IEA
GO:0045087	innate immune response	Biological Process	IEA