ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Kcnj10

Full Name:

potassium inwardly-rectifying channel, subfamily J, member 10

Alias:

BIR10|BIRK-1|Kir1.2|Kir4.1

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

1 H3|1 93.5 cM

Physical Location:

174271340-174304215 on NC_000067.5

Gene Type:

protein-coding

Human Ortholog:

GeneID: 3766 Symbol (Name): KCNJ10 (potassium inwardly-rectifying channel, subfamily J, member 10)

Ortholog Status:

The human GeneID 3766 is also in human dataset(s).

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Alcw1	Acute Alcohol Withdrawal	1	96	172.3-176.5 (Mb)	5.6	3.00E-07	Significant	PARC
Calw1/Alcdp1	Chronic Alcohol Withdrawal	1	96	89-106.3 (cM)	7.6	2.00E-09	Significant	PARC
Ap1q	Alcohol Preference Drinking	1	76	45-95 (cM)	4.5		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_001039484.1	NP_001034573.1	NC_000067.5 range: 174271340..174304215

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005887	integral to plasma membrane	Cellular Component	IC (9647694)
GO:0016021	integral to membrane	Cellular Component	RCA (12466851)
GO:0016020	membrane	Cellular Component	IEA
GO:0000166	nucleotide binding	Molecular Function	IEA
GO:0005524	ATP binding	Molecular Function	IEA
GO:0005515	protein binding	Molecular Function	IPI (9647694)
GO:0005267	potassium channel activity	Molecular Function	IDA (9647694)
GO:0005244	voltage-gated ion channel activity	Molecular Function	IEA
GO:0005242	inward rectifier potassium channel activity	Molecular Function	IEA
GO:0005216	ion channel activity	Molecular Function	IEA
GO:0030955	potassium ion binding	Molecular Function	IEA
GO:0006810	transport	Biological Process	IEA
GO:0006811	ion transport	Biological Process	IEA
GO:0006813	potassium ion transport	Biological Process	IDA (9647694)