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Gene Information
Gene ID:19224
Symbol:Ptgs1
Full Name:prostaglandin-endoperoxide synthase 1
Alias:COX1|Cox-1|Cox-3|Pghs1
Organism:Mus musculus (Mouse)
Chromosome:2
Genetic Location:2 B|2 29.0 cM
Physical Location:36085945-36107788 on NC_000068.6
Gene Type:protein-coding
Human Ortholog:GeneID: 5742    Symbol (Name): PTGS1 (prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase))
Ortholog Status:The human GeneID 5742 is also in human dataset(s).
Gene in Ethanol Study Datasets
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Alcp1Alcohol Preference Drinking22819-35 (cM)5.3 SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_008969.3NP_032995.1NC_000068.6 range: 36085945..36107788
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0016020membraneCellular ComponentIEA
GO:0005792microsomeCellular ComponentIDA (12021206)
GO:0005783endoplasmic reticulumCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIDA (12021206)
GO:0005634nucleusCellular ComponentIDA (12021206)
GO:0005615extracellular spaceCellular ComponentRCA (12466851)
GO:0005506iron ion bindingMolecular FunctionIEA
GO:0004666prostaglandin-endoperoxide synthase activityMolecular FunctionIEA
GO:0004601peroxidase activityMolecular FunctionIEA
GO:0020037heme bindingMolecular FunctionIEA
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenMolecular FunctionIEA
GO:0016491oxidoreductase activityMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0030216keratinocyte differentiationBiological ProcessNAS (12067981)
GO:0008610lipid biosynthetic processBiological ProcessIEA
GO:0008217regulation of blood pressureBiological ProcessIMP (12093889)
GO:0006979response to oxidative stressBiological ProcessIEA
GO:0006633fatty acid biosynthetic processBiological ProcessIEA
GO:0001516prostaglandin biosynthetic processBiological ProcessIMP (12093889)
Other Database Cross Links
NCBI Entrez Gene:19224
MGI:MGI:97797
Ensembl:ENSMUSG00000047250
dbSNP:Ptgs1
AceView:Ptgs1