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Gene Information
Gene ID:398
Symbol:ARHGDIG
Full Name:Rho GDP dissociation inhibitor (GDI) gamma
Alias:RHOGDI-3
Organism:Homo sapiens (Human)
Chromosome:16
Genetic Location:16p13.3
Physical Location:270606-273003 on NC_000016.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:U82532
Fold Change:1.4, 2.4
Note:Differential expression on the oligonucleotide array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001176.2NP_001167.2NC_000016.8 range: 270606..273003
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005737cytoplasmCellular ComponentIEA
GO:0016023cytoplasmic membrane-bounded vesicleCellular ComponentTAS (9113980)
GO:0005094Rho GDP-dissociation inhibitor activityMolecular FunctionTAS (9113980)
GO:0005096GTPase activator activityMolecular FunctionIEA
GO:0007162negative regulation of cell adhesionBiological ProcessTAS (9113980)
GO:0007266Rho protein signal transductionBiological ProcessTAS (9113980)
Other Database Cross Links
NCBI Entrez Gene:398
HGNC:680
Ensembl:ENSG00000206156
MIM:602844
HPRD:04163
HuGE Navigator:398
dbSNP:ARHGDIG
GeneCard:ARHGDIG
AceView:ARHGDIG