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Gene Information
Gene ID:5977
Symbol:DPF2
Full Name:D4, zinc and double PHD fingers family 2
Alias:MGC10180|REQ|UBID4|ubi-d4
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11q13
Physical Location:64857921-64877026 on NC_000011.8
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AF001433
Fold Change:-1.5, -1.5
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_006268.3NP_006259.1NC_000011.8 range: 64857921..64877026
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005622intracellularCellular ComponentIEA
GO:0005634nucleusCellular ComponentIEA
GO:0005737cytoplasmCellular ComponentIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0008270zinc ion bindingMolecular FunctionIEA
GO:0046872metal ion bindingMolecular FunctionIEA
GO:0006915apoptosisBiological ProcessIEA
GO:0006350transcriptionBiological ProcessIEA
GO:0008624induction of apoptosis by extracellular signalsBiological ProcessTAS (7961935)
GO:0006355regulation of transcription, DNA-dependentBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:5977
HGNC:9964
Ensembl:ENSG00000133884
MIM:601671
HPRD:03394
HuGE Navigator:5977
dbSNP:DPF2
GeneCard:DPF2
AceView:DPF2