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Gene Information
Gene ID:65247
Full Name:ankyrin repeat and SOCS box-containing protein 1
Organism:Mus musculus (Mouse)
Genetic Location:1 D|1 57.0 cM
Physical Location:93437141-93456166 on NC_000067.5
Gene Type:protein-coding
Human Ortholog:GeneID: 51665    Symbol (Name): ASB1 (ankyrin repeat and SOCS box-containing 1)
Ortholog Status:The human GeneID 51665 is also in human dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:Asb1
Dataset Information
Tissue:Whole brain
Phenotype:Alcohol preference
Publication:Mulligan et al. Proc Natl Acad Sci U S A. (2006) Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. PubMed
Summary:Microarray analyses of brain gene expression in three selected lines, and six isogenic strains of mice known to differ markedly in voluntary alcohol consumption provided >4.5 million data points for a meta-analysis. A total of 107 arrays were obtained and arranged into six experimental data sets, allowing the identification of 3,800 unique genes significantly and consistently changed between all models of high or low amounts of alcohol consumption. Here we select the 75 genes with the largest effect size (|d|) and lowest Q values.
QTL Information
QTLPhenotypeChrPeak (cM)LODP ValueRangeStatusQTL Link
Ap1qAlcohol Preference Drinking17645-95 (cM)4.5 SignificantPARC
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001039126.2NP_001034215.1NC_000067.5 range: 93437141..93456166
NM_023046.4NP_075533.3NC_000067.5 range: 93437141..93456166
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005575cellular_componentCellular ComponentND
GO:0006512ubiquitin cycleBiological ProcessIEA
GO:0007242intracellular signaling cascadeBiological ProcessIEA
GO:0007275multicellular organismal developmentBiological ProcessIEA
GO:0030539male genitalia developmentBiological ProcessIMP (11509662)
Other Database Cross Links
NCBI Entrez Gene:65247