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Gene Information
Gene ID:8642
Symbol:DCHS1
Full Name:dachsous 1 (Drosophila)
Alias:CDH25|FIB1|FLJ11790|KIAA1773|PCDH16
Organism:Homo sapiens (Human)
Chromosome:11
Genetic Location:11p15.4
Physical Location:6599133-6633655 on NC_000011.8, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:AI018181
Fold Change:1.4, 1.8
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_003737.2NP_003728.1NC_000011.8 range: 6599133..6633655, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005886plasma membraneCellular ComponentIEA
GO:0016021integral to membraneCellular ComponentIEA
GO:0005509calcium ion bindingMolecular FunctionIEA
GO:0005515protein bindingMolecular FunctionIEA
GO:0007155cell adhesionBiological ProcessIEA
GO:0007156homophilic cell adhesionBiological ProcessIEA
GO:0016339calcium-dependent cell-cell adhesionBiological ProcessNAS (9199196)
Other Database Cross Links
NCBI Entrez Gene:8642
HGNC:13681
Ensembl:ENSG00000166341
MIM:603057
HPRD:04341
HuGE Navigator:8642
dbSNP:DCHS1
GeneCard:DCHS1
AceView:DCHS1