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Gene Information
Gene ID:9783
Symbol:RIMS3
Full Name:regulating synaptic membrane exocytosis 3
Alias:KIAA0237|NIM3|RIM3
Organism:Homo sapiens (Human)
Chromosome:1
Genetic Location:1pter-p22.2
Physical Location:40858938-40903914 on NC_000001.9, complement
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Gene Information
Original ID1:D87074
Fold Change:1.4, 1.6
Note:Differential Expression on the cDNA array (two fold changes are from two case groups)
Dataset Information
Name:11141048
Method:Microarray
Tissue:Frontal cortex
Phenotype:Alcohol dependence (AD)/Alcohol abuse/Alcoholism
Publication:Lewohl et al. Alcohol Clin Exp Res. (2000) Gene expression in human alcoholism: microarray analysis of frontal cortex. PubMed
Summary:RNA was extracted from postmortem samples of superior frontal cortex of alcoholics and nonalcoholics. Relative levels of RNA were determined by array techniques. This study used both cDNA and oligonucleotide microarrays to provide coverage of a large number of genes and to allow cross-validation for those genes represented on both types of arrays. Expression levels were determined for over 4000 genes and 163 of these were found to differ by 40% or more between alcoholics and nonalcoholics.
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_014747.2NP_055562.2NC_000001.9 range: 40858938..40903914, complement
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0030054cell junctionCellular ComponentIEA
GO:0045202synapseCellular ComponentIEA
GO:0006836neurotransmitter transportBiological ProcessIEA
GO:0006887exocytosisBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:9783
HGNC:21292
Ensembl:ENSG00000117016
MIM:611600
HPRD:17976
HuGE Navigator:9783
dbSNP:RIMS3
GeneCard:RIMS3
AceView:RIMS3