Gene Page: NDC80

Summary
GeneID  10403
Symbol  NDC80
Synonyms  HEC|HEC1|KNTC2|TID3|hsNDC80
Description  NDC80 homolog, kinetochore complex component (S. cerevisiae)
See related  HGNC:16909|MIM:607272|Ensembl:ENSG00000080986|HPRD:06277|
Locus tag  -
Gene type  protein-coding
Map location  18p11.32
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0057 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI14699129 |15713649 |15961401 
|16732327 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000070mitotic sister chromatid segregationTAS9315664 
GO:0007049cell cycleNAS15504738 
GO:0007051spindle organizationNAS15504738 
GO:0048015phosphoinositide-mediated signalingNAS15504738 
GO:0051301cell divisionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000775chromosome, centromeric regionTAS9315664 
GO:0000777condensed chromosome kinetochoreIEA-
GO:0005634nucleusTAS9315664 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
AMOTL2LCCPangiomotin like 2Two-hybridBioGRID16189514 
CALCOCO1Cocoa | KIAA1536 | PP13275 | calphoglincalcium binding and coiled-coil domain 1Two-hybridBioGRID16189514 
CCDC53CGI-116coiled-coil domain containing 53Two-hybridBioGRID16189514 
KLHL12C3IP1 | DKIR | FLJ27152kelch-like 12 (Drosophila)Two-hybridBioGRID16189514 
MAD1L1HsMAD1 | MAD1 | PIG9 | TP53I9 | TXBP181MAD1 mitotic arrest deficient-like 1 (yeast)-HPRD12351790 
MAD2L1HSMAD2 | MAD2MAD2 mitotic arrest deficient-like 1 (yeast)-HPRD12351790 
MIS122510025F08Rik | KNTC2AP | MGC2488 | MTW1 | hMis12MIS12, MIND kinetochore complex component, homolog (yeast)-HPRD,BioGRID15502821 
NEK2HsPK21 | NEK2A | NLK1NIMA (never in mitosis gene a)-related kinase 2-HPRD,BioGRID12386167 
NUF2CDCA1 | NUF2RNUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)Affinity Capture-MSBioGRID14699129 
PLDNPA | PALLIDpallidin homolog (mouse)Two-hybridBioGRID16189514 
RB1OSRC | RB | p105-Rb | pRb | pp110retinoblastoma 1-HPRD,BioGRID10409732 
SMC1ACDLS2 | DKFZp686L19178 | DXS423E | KIAA0178 | MGC138332 | SB1.8 | SMC1 | SMC1L1 | SMC1alpha | SMCBstructural maintenance of chromosomes 1A-HPRD,BioGRID9295362 
SPC24FLJ90806 | SPBC24SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)Affinity Capture-MSBioGRID14699129 
SPC25AD024 | MGC22228 | SPBC25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)-HPRD,BioGRID14699129 
TOM1L1OK/KNS-CL.3 | SRCASMtarget of myb1 (chicken)-like 1Two-hybridBioGRID16169070 
USHBP1AIEBP | FLJ38709 | FLJ90681 | MCC2Usher syndrome 1C binding protein 1Two-hybridBioGRID16189514 
 


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