Gene Page: CHRM3

Summary
GeneID  1131
Symbol  CHRM3
Synonyms  HM3
Description  cholinergic receptor, muscarinic 3
See related  HGNC:1952|MIM:118494|Ensembl:ENSG00000133019|HPRD:00329|
Locus tag  -
Gene type  protein-coding
Map location  1q43
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0018 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004435phosphoinositide phospholipase C activityTAS1905013 
GO:0004872receptor activityTAS10940357 
GO:0004981muscarinic acetylcholine receptor activityTAS9547368 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006464protein modification processTAS10051746 
GO:0007165signal transductionTAS10940357 
GO:0007186G-protein coupled receptor protein signaling pathwayTAS9603968 
GO:0007399nervous system developmentTASneurite (GO term level: 5)2739737 
GO:0007586digestionIEA-
GO:0008283cell proliferationTAS8063729 
GO:0045987positive regulation of smooth muscle contractionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneTAS9547368 
GO:0005887integral to plasma membraneTAS3443095 
GO:0016323basolateral plasma membraneIEA-
GO:0030054cell junctionIEA-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ARF1-ADP-ribosylation factor 1Affinity Capture-Western
Reconstituted Complex
BioGRID12799371 
ARF6DKFZp564M0264ADP-ribosylation factor 6-HPRD,BioGRID12799371 
CSNK1A1CK1 | HLCDGP1 | PRO2975casein kinase 1, alpha 1-HPRD,BioGRID10777483 
GNAQG-ALPHA-q | GAQguanine nucleotide binding protein (G protein), q polypeptide-HPRD7629074 
GRK6FLJ32135 | GPRK6G protein-coupled receptor kinase 6-HPRD11856737 
GZMBCCPI | CGL-1 | CGL1 | CSP-B | CSPB | CTLA1 | CTSGL1 | HLP | SECTgranzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)-HPRD,BioGRID11665980 
 
KEGG Pathway Info
hsa04020: Calcium signaling pathway - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa04080: Neuroactive ligand-receptor interaction - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa04810: Regulation of actin cytoskeleton - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 


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