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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: EFNB1

Summary

GeneID

1947

Symbol

EFNB1

Synonyms

Description

ephrin-B1

Locus tag

RP3-496G1.1

Gene type

protein-coding

Map location

Xq12

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 2

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0172

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005515

protein binding

IPI

9883737

GO:0005515

protein binding

ISS

GO:0046875

ephrin receptor binding

TAS

8798744

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0001755

neural crest cell migration

IEA

GO:0007155

cell adhesion

TAS

8798744

GO:0007267

cell-cell signaling

TAS

8798744

GO:0007275

multicellular organismal development

IEA

GO:0007399

nervous system development

IEA

neurite (GO term level: 5)

GO:0007411

axon guidance

IEA

axon (GO term level: 13)

GO:0009880

embryonic pattern specification

IEA

GO:0030154

cell differentiation

IEA

GO:0042102

positive regulation of T cell proliferation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005625

soluble fraction

TAS

8798744

GO:0005887

integral to plasma membrane

TAS

8660976

GO:0016020

membrane

IEA

GO:0045121

membrane raft

IEA

GO:0045202

synapse

ISS

neuron, Synap, Neurotransmitter, Glial (GO term level: 2)

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
EPHA3	ETK \| ETK1 \| HEK \| HEK4 \| TYRO4	EPH receptor A3	Reconstituted Complex	BioGRID	9195962
EPHB1	ELK \| EPHT2 \| FLJ37986 \| Hek6 \| NET	EPH receptor B1	The membrane bound ligand ELK-L interacts with the receptor ELK. This interaction was modeled on a demonstrated interaction between ELK-L from human and ELK from rat.	BIND	7973638 \|8755474
EPHB1	ELK \| EPHT2 \| FLJ37986 \| Hek6 \| NET	EPH receptor B1	-	HPRD,BioGRID	10669731 \|12223469
EPHB2	CAPB \| DRT \| EPHT3 \| ERK \| Hek5 \| MGC87492 \| PCBC \| Tyro5	EPH receptor B2	-	HPRD	8878483
EPHB2	CAPB \| DRT \| EPHT3 \| ERK \| Hek5 \| MGC87492 \| PCBC \| Tyro5	EPH receptor B2	The membrane bound ligand ELK-L interacts with the receptor NUK. This interaction was modeled on a demonstrated interaction between ELK-L from human and NUK from mouse.	BIND	8755474
GRIP2	-	glutamate receptor interacting protein 2	in vitro in vivo Two-hybrid	BioGRID	9883737 \|10197531
NCK2	GRB4 \| NCKbeta	NCK adaptor protein 2	-	HPRD	11557983
PICK1	MGC15204 \| PICK \| PRKCABP	protein interacting with PRKCA 1	-	HPRD,BioGRID	9883737
PTPN13	DKFZp686J1497 \| FAP-1 \| PNP1 \| PTP-BAS \| PTP-BL \| PTP1E \| PTPL1 \| PTPLE	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	-	HPRD,BioGRID	9920925
RGS3	C2PA \| FLJ20370 \| FLJ31516 \| FLJ90496 \| PDZ-RGS3 \| RGP3	regulator of G-protein signaling 3	-	HPRD,BioGRID	11301003
SDCBP	MDA-9 \| ST1 \| SYCL \| TACIP18	syndecan binding protein (syntenin)	-	HPRD,BioGRID	9920925
SORBS1	CAP \| DKFZp451C066 \| DKFZp586P1422 \| FLAF2 \| FLJ12406 \| KIAA1296 \| R85FL \| SH3D5 \| SH3P12 \| SORB1	sorbin and SH3 domain containing 1	-	HPRD	11557983
SRC	ASV \| SRC1 \| c-SRC \| p60-Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	-	HPRD,BioGRID	8878483

KEGG Pathway Info

hsa04360: Axon guidance - Homo sapiens (human)

Go to KEGG

All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-103/107	834	840	1A	hsa-miR-103^brain	AGCAGCAUUGUACAGGGCUAUGA
miR-103/107	834	840	1A	hsa-miR-107^brain	AGCAGCAUUGUACAGGGCUAUCA
miR-124/506	200	206	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	200	206	m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-129-5p	730	736	1A	hsa-miR-129^brain	CUUUUUGCGGUCUGGGCUUGC
miR-129-5p	730	736	1A	hsa-miR-129-5p	CUUUUUGCGGUCUGGGCUUGCU
miR-140	1496	1502	1A	hsa-miR-140^brain	AGUGGUUUUACCCUAUGGUAG
miR-15/16/195/424/497	1178	1184	1A	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-150	1303	1309	1A	hsa-miR-150	UCUCCCAACCCUUGUACCAGUG
miR-17-5p/20/93.mr/106/519.d	1148	1154	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-185	936	942	m8	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-208	799	805	1A	hsa-miR-208	AUAAGACGAGCAAAAAGCUUGU
miR-34/449	1189	1195	1A	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-381	1425	1431	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-491	63	69	1A	hsa-miR-491^brain	AGUGGGGAACCCUUCCAUGAGGA
miR-496	1412	1418	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-499	799	805	1A	hsa-miR-499	UUAAGACUUGCAGUGAUGUUUAA
miR-503	1178	1184	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.