Gene Page

Gene Page: EGR2

Summary

GeneID

1959

Symbol

EGR2

Synonyms

Description

early growth response 2 (Krox-20 homolog, Drosophila)

Locus tag

Gene type

protein-coding

Map location

10q21.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IDA

14532282

GO:0005515

protein binding

IPI

14532282

GO:0008270

zinc ion binding

IEA

GO:0046872

metal ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006350

transcription

IEA

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0007420

brain development

TAS

Brain (GO term level: 7)

9537424

GO:0007422

peripheral nervous system development

TAS

9537424

GO:0007638

mechanosensory behavior

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0005634

nucleus

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACP5	MGC117378 \| TRAP	acid phosphatase 5, tartrate resistant	Two-hybrid	BioGRID	16169070
FASLG	APT1LG1 \| CD178 \| CD95L \| FASL \| TNFSF6	Fas ligand (TNF superfamily, member 6)	EGR2 interacts with p-FasL (FasL promoter).	BIND	11909874
HCFC1	CFF \| HCF-1 \| HCF1 \| HFC1 \| MGC70925 \| VCAF	host cell factor C1 (VP16-accessory protein)	-	HPRD,BioGRID	14532282
MED31	3110004H13Rik \| CGI-125 \| FLJ27436 \| FLJ36714 \| Soh1	mediator complex subunit 31	Two-hybrid	BioGRID	16169070
NFATC1	MGC138448 \| NF-ATC \| NFAT2 \| NFATc	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	Reconstituted Complex	BioGRID	12560487

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124.1	907	913	m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	858	864	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
				hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
				hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-137	579	586	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-137	579	586	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-141/200a	1029	1035	1A	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	1029	1035	1A	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-142-3p	73	79	m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-150	401	408	1A,m8	hsa-miR-150	UCUCCCAACCCUUGUACCAGUG
miR-17-5p/20/93.mr/106/519.d	458	465	1A,m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-224	1019	1026	1A,m8	hsa-miR-224	CAAGUCACUAGUGGUUCCGUUUA
miR-25/32/92/363/367	612	618	m8	hsa-miR-25^brain	CAUUGCACUUGUCUCGGUCUGA
				hsa-miR-32	UAUUGCACAUUACUAAGUUGC
				hsa-miR-92	UAUUGCACUUGUCCCGGCCUG
				hsa-miR-367	AAUUGCACUUUAGCAAUGGUGA
				hsa-miR-92b^SZ	UAUUGCACUCGUCCCGGCCUC
miR-324-5p	826	832	1A	hsa-miR-324-5p	CGCAUCCCCUAGGGCAUUGGUGU
miR-34b	962	968	1A	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-377	864	870	m8	hsa-miR-377	AUCACACAAAGGCAACUUUUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.