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GeneID
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2900
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Symbol
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GRIK4 |
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Synonyms
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EAA1|GRIK|KA1 |
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Description
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glutamate receptor, ionotropic, kainate 4 |
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See related
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HGNC:4582|MIM:600282|Ensembl:ENSG00000149403|HPRD:02613| |
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Locus tag
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- |
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Gene type
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protein-coding |
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Map location
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11q22.3 |
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| Gene set name | Method of gene set | Evidence | Info |
|---|
| Association | A combined odds ratio method (Sun et al. 2008), association studies | 1 | Link to SZGene | | GSMA_I | genome scan meta-analysis | Psr: 0.006 | | | Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia] | Click to show detail | | GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 7 | | | Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 31 | |
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| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0004872 | receptor activity | IEA | | - |
| GO:0005216 | ion channel activity | IEA | | - |
| GO:0005234 | extracellular-glutamate-gated ion channel activity | IEA | glutamate (GO term level: 11) | - |
| GO:0005515 | protein binding | IEA | | - |
| GO:0015277 | kainate selective glutamate receptor activity | TAS | glutamate (GO term level: 8) | 8263508 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0006811 | ion transport | IEA | | - |
| GO:0007215 | glutamate signaling pathway | TAS | glutamate (GO term level: 7) | 8263508 |
| GO:0007268 | synaptic transmission | TAS | neuron, Synap, Neurotransmitter (GO term level: 6) | 8263508 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005624 | membrane fraction | IEA | | - |
| GO:0005886 | plasma membrane | IEA | | - |
| GO:0005887 | integral to plasma membrane | TAS | | 8263508 |
| GO:0030054 | cell junction | IEA | | - |
| GO:0032983 | kainate selective glutamate receptor complex | IEA | glutamate (GO term level: 10) | - |
| GO:0042734 | presynaptic membrane | IEA | neuron, axon, Synap (GO term level: 5) | - |
| GO:0045202 | synapse | IEA | neuron, Synap, Neurotransmitter, Glial (GO term level: 2) | - |
| GO:0045211 | postsynaptic membrane | IEA | Synap, Neurotransmitter (GO term level: 5) | - |
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