Gene Page: GRIK4

Summary
GeneID  2900
Symbol  GRIK4
Synonyms  EAA1|GRIK|KA1
Description  glutamate receptor, ionotropic, kainate 4
See related  HGNC:4582|MIM:600282|Ensembl:ENSG00000149403|HPRD:02613|
Locus tag  -
Gene type  protein-coding
Map location  11q22.3
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
AssociationA combined odds ratio method (Sun et al. 2008), association studies1Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.006 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 7 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 31 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0005216ion channel activityIEA-
GO:0005234extracellular-glutamate-gated ion channel activityIEAglutamate (GO term level: 11)-
GO:0005515protein bindingIEA-
GO:0015277kainate selective glutamate receptor activityTASglutamate (GO term level: 8)8263508 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006811ion transportIEA-
GO:0007215glutamate signaling pathwayTASglutamate (GO term level: 7)8263508 
GO:0007268synaptic transmissionTASneuron, Synap, Neurotransmitter (GO term level: 6)8263508 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005624membrane fractionIEA-
GO:0005886plasma membraneIEA-
GO:0005887integral to plasma membraneTAS8263508 
GO:0030054cell junctionIEA-
GO:0032983kainate selective glutamate receptor complexIEAglutamate (GO term level: 10)-
GO:0042734presynaptic membraneIEAneuron, axon, Synap (GO term level: 5)-
GO:0045202synapseIEAneuron, Synap, Neurotransmitter, Glial (GO term level: 2)-
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
GRIK2EAA4 | GLR6 | GLUK6 | GLUR6 | MGC74427 | MRT6glutamate receptor, ionotropic, kainate 2-HPRD8288598 |12954862 
 
KEGG Pathway Info
hsa04080: Neuroactive ligand-receptor interaction - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 


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