Gene Page: BRF1

Summary
GeneID  2972
Symbol  BRF1
Synonyms  BRF|FLJ42674|FLJ43034|GTF3B|MGC105048|TAF3B2|TAF3C|TAFIII90|TF3B90|TFIIIB90|hBRF
Description  BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)
See related  HGNC:11551|MIM:604902|Ensembl:ENSG00000185024|HPRD:05361|
Locus tag  -
Gene type  protein-coding
Map location  14q
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.8442 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityNAS-
GO:0003709RNA polymerase III transcription factor activityTAS8943358 
GO:0003743translation initiation factor activityIEA-
GO:0005515protein bindingIEA-
GO:0005515protein bindingTAS7624363 
GO:0008270zinc ion bindingIEA-
GO:0016563transcription activator activityIEA-
GO:0030528transcription regulator activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006352transcription initiationIEA-
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006384transcription initiation from RNA polymerase III promoterTAS7624363 
GO:0006413translational initiationIEA-
GO:0009303rRNA transcriptionTAS7624363 
GO:0009304tRNA transcriptionTAS8943358 
GO:0045941positive regulation of transcriptionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000126transcription factor TFIIIB complexNAS8943358 
GO:0005634nucleusIEA-
GO:0005667transcription factor complexIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CSNK2A1CK2A1 | CKIIcasein kinase 2, alpha 1 polypeptide-HPRD,BioGRID11997511 
CSNK2A2CK2A2 | CSNK2A1 | FLJ43934casein kinase 2, alpha prime polypeptideAffinity Capture-WesternBioGRID11997511 
GTF3C3TFIIIC102 | TFIIICgamma | TFiiiC2-102general transcription factor IIIC, polypeptide 3, 102kDa-HPRD,BioGRID10373544 
GTF3C4FLJ21002 | KAT12 | MGC138450 | TFIII90 | TFIIIC90 | TFIIICdelta | TFiiiC2-90general transcription factor IIIC, polypeptide 4, 90kDa-HPRD10523658 
GTF3C5FLJ20857 | TFIIIC63 | TFIIICepsilon | TFiiiC2-63general transcription factor IIIC, polypeptide 5, 63kDaAffinity Capture-WesternBioGRID10373544 
POLR3FMGC13517 | RPC39 | RPC6polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa-HPRD9171375 
RB1OSRC | RB | p105-Rb | pRb | pp110retinoblastoma 1Affinity Capture-WesternBioGRID11997511 
RBL1CP107 | MGC40006 | PRB1 | p107retinoblastoma-like 1 (p107)-HPRD,BioGRID10330166 
TBPGTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIIDTATA box binding protein-HPRD,BioGRID7624363 |10921893 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53-HPRD,BioGRID8943363 
 


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