Gene Page

Gene Page: ARNTL

Summary

GeneID

406

Symbol

ARNTL

Synonyms

BMAL1|BMAL1c|JAP3|MGC47515|MOP3|PASD3|TIC|bHLHe5

Description

aryl hydrocarbon receptor nuclear translocator-like

Locus tag

Gene type

protein-coding

Map location

11p15

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003700

transcription factor activity

IEA

GO:0004871

signal transducer activity

IEA

GO:0017162

aryl hydrocarbon receptor binding

IPI

9079689

GO:0051879

Hsp90 protein binding

IDA

9079689

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006355

regulation of transcription, DNA-dependent

IEA

GO:0007165

signal transduction

IEA

GO:0007623

circadian rhythm

TAS

9616112

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

IGI

9576906

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005634

nucleus

IEA

GO:0005667

transcription factor complex

IPI

9576906

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
AHR	-	aryl hydrocarbon receptor	-	HPRD,BioGRID	9079689
BHLHB2	DEC1 \| SHARP-2 \| STRA13 \| Stra14 \| bHLHe40	basic helix-loop-helix domain containing, class B, 2	-	HPRD	12397359
CLOCK	KAT13D \| KIAA0334 \| bHLHe8	clock homolog (mouse)	Two-hybrid	BioGRID	11439184 \|14701734
CLOCK	KAT13D \| KIAA0334 \| bHLHe8	clock homolog (mouse)	-	HPRD	9989497
CRY1	PHLL1	cryptochrome 1 (photolyase-like)	-	HPRD,BioGRID	10531061
CSNK1E	HCKIE \| MGC10398	casein kinase 1, epsilon	-	HPRD,BioGRID	11875063
EP300	KAT3B \| p300	E1A binding protein p300	Reconstituted Complex	BioGRID	14645221
EPAS1	ECYT4 \| HIF2A \| HLF \| MOP2 \| PASD2	endothelial PAS domain protein 1	-	HPRD,BioGRID	9576906
HIF1A	HIF-1alpha \| HIF1 \| HIF1-ALPHA \| MOP1 \| PASD8	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	-	HPRD,BioGRID	9576906
HSP90AA1	FLJ31884 \| HSP86 \| HSP89A \| HSP90A \| HSP90N \| HSPC1 \| HSPCA \| HSPCAL1 \| HSPCAL4 \| HSPN \| Hsp89 \| Hsp90 \| LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	-	HPRD,BioGRID	9079689
KAT2B	CAF \| P \| P/CAF \| PCAF	K(lysine) acetyltransferase 2B	Reconstituted Complex	BioGRID	14645221
NPAS2	FLJ23138 \| MGC71151 \| MOP4 \| PASD4 \| bHLHe9	neuronal PAS domain protein 2	in vitro in vivo Two-hybrid	BioGRID	9576906 \|11439184
NPAS4	Le-PAS \| NXF \| PASD10	neuronal PAS domain protein 4	-	HPRD,BioGRID	14701734
RARA	NR1B1 \| RAR	retinoic acid receptor, alpha	Reconstituted Complex	BioGRID	11439184
RXRA	FLJ00280 \| FLJ00318 \| FLJ16020 \| FLJ16733 \| MGC102720 \| NR2B1	retinoid X receptor, alpha	Reconstituted Complex	BioGRID	11439184

KEGG Pathway Info

hsa04710: Circadian rhythm - Homo sapiens (human)

Go to KEGG

All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-141/200a	193	199	m8	hsa-miR-141	UAACACUGUCUGGUAAAGAUGG
miR-141/200a	193	199	m8	hsa-miR-200a	UAACACUGUCUGGUAACGAUGU
miR-142-3p	352	359	1A,m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-153	317	323	1A	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-155	238	244	1A	hsa-miR-155	UUAAUGCUAAUCGUGAUAGGGG
miR-203.1	329	335	1A	hsa-miR-203	UGAAAUGUUUAGGACCACUAG
miR-27	65	71	1A	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	65	71	1A	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC
miR-381	245	251	1A	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-448	316	323	1A,m8	hsa-miR-448	UUGCAUAUGUAGGAUGUCCCAU
miR-494	490	496	m8	hsa-miR-494^brain	UGAAACAUACACGGGAAACCUCUU
miR-505	267	274	1A,m8	hsa-miR-505	GUCAACACUUGCUGGUUUCCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.