Gene Page

Gene Page: PLXNA2

Summary

GeneID

5362

Symbol

PLXNA2

Synonyms

FLJ11751|FLJ30634|KIAA0463|OCT|PLXN2

Description

plexin A2

Locus tag

RP11-328D5.3

Gene type

protein-coding

Map location

1q32.2

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Association

A combined odds ratio method (Sun et al. 2008), association studies

Link to SZGene

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 31

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004872

receptor activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007165

signal transduction

IEA

GO:0007275

multicellular organismal development

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005622

intracellular

IEA

GO:0016020

membrane

IEA

GO:0016021

integral to membrane

IEA

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
DHX37	DDX37 \| FLJ41974 \| KIAA1517 \| MGC2695 \| MGC4322 \| MGC46245	DEAH (Asp-Glu-Ala-His) box polypeptide 37	-	HPRD	12421765
HACE1	-	HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1	-	HPRD	12421765
IFT80	ATD2 \| KIAA1374 \| MGC126543 \| WDR56	intraflagellar transport 80 homolog (Chlamydomonas)	-	HPRD	12421765
KIAA1199	TMEM2L	KIAA1199	-	HPRD	12421765

KEGG Pathway Info

hsa04360: Axon guidance - Homo sapiens (human)

Go to KEGG

All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	4940	4946	m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-137	1174	1181	1A,m8	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-142-5p	352	358	m8	hsa-miR-142-5p	CAUAAAGUAGAAAGCACUAC
miR-145	4730	4736	1A	hsa-miR-145	GUCCAGUUUUCCCAGGAAUCCCUU
miR-15/16/195/424/497	302	308	m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-199	4728	4735	1A,m8	hsa-miR-199a	CCCAGUGUUCAGACUACCUGUUC
miR-199	4728	4735	1A,m8	hsa-miR-199b	CCCAGUGUUUAGACUAUCUGUUC
miR-214	3780	3787	1A,m8	hsa-miR-214^brain	ACAGCAGGCACAGACAGGCAG
miR-26	1180	1187	1A,m8	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	1180	1187	1A,m8	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-30-5p	1164	1171	1A,m8	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-31	2052	2058	m8	hsa-miR-31	AGGCAAGAUGCUGGCAUAGCUG
miR-326	92	98	m8	hsa-miR-326	CCUCUGGGCCCUUCCUCCAG
miR-330	305	311	m8	hsa-miR-330^brain	GCAAAGCACACGGCCUGCAGAGA
miR-369-3p	4740	4747	1A,m8	hsa-miR-369-3p	AAUAAUACAUGGUUGAUCUUU
miR-374	4741	4747	m8	hsa-miR-374	UUAUAAUACAACCUGAUAAGUG
miR-378	2105	2111	1A	hsa-miR-378	CUCCUGACUCCAGGUCCUGUGU
miR-410	4948	4955	1A,m8	hsa-miR-410	AAUAUAACACAGAUGGCCUGU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.