Gene Page: PPT1

Summary
GeneID  5538
Symbol  PPT1
Synonyms  CLN1|INCL|PPT
Description  palmitoyl-protein thioesterase 1
See related  HGNC:9325|MIM:600722|Ensembl:ENSG00000131238|HPRD:07203|
Locus tag  RP11-115D7.2
Gene type  protein-coding
Map location  1p32
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 11 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008474palmitoyl-(protein) hydrolase activityIDA10658183 |10737604 
GO:0008474palmitoyl-(protein) hydrolase activityIEA-
GO:0008474palmitoyl-(protein) hydrolase activityIMP7637805 
GO:0008474palmitoyl-(protein) hydrolase activityISS-
GO:0016290palmitoyl-CoA hydrolase activityIDA10658183 
GO:0016290palmitoyl-CoA hydrolase activityISS-
GO:0016787hydrolase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002084protein depalmitoylationIDA10658183 |10737604 
GO:0002084protein depalmitoylationISS-
GO:0006309DNA fragmentation during apoptosisIDA15929065 
GO:0006464protein modification processIEA-
GO:0007042lysosomal lumen acidificationIMP11722572 
GO:0007269neurotransmitter secretionIEAneuron, axon, Synap, serotonin, Neurotransmitter, dopamine (GO term level: 8)-
GO:0007399nervous system developmentIMPneurite (GO term level: 5)7637805 
GO:0007420brain developmentIEPBrain (GO term level: 7)10992246 
GO:0007420brain developmentIMPBrain (GO term level: 7)7637805 
GO:0007601visual perceptionIEA-
GO:0007625grooming behaviorIEA-
GO:0008306associative learningIEA-
GO:0008344adult locomotory behaviorIEA-
GO:0015031protein transportIMP10737604 
GO:0016042lipid catabolic processIDA8816748 
GO:0030149sphingolipid catabolic processTAS16542649 
GO:0030308negative regulation of cell growthIMP10737604 
GO:0031579membrane raft organizationIMP15929065 
GO:0032429regulation of phospholipase A2 activityIEA-
GO:0043524negative regulation of neuron apoptosisIMPneuron (GO term level: 9)10737604 |11020216 
GO:0044257cellular protein catabolic processIEA-
GO:0048260positive regulation of receptor-mediated endocytosisIMP16542649 
GO:0048549positive regulation of pinocytosisIMP16542649 
GO:0048666neuron developmentTASneuron (GO term level: 9)11136716 
GO:0050803regulation of synapse structure and activityNASneuron, Synap (GO term level: 7)11136716 
GO:0050896response to stimulusIEA-
GO:0051181cofactor transportIMP16542649 
GO:0051186cofactor metabolic processIMP16542649 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIDA8895569 
GO:0005576extracellular regionISS-
GO:0005615extracellular spaceIEA-
GO:0005624membrane fractionISS-
GO:0005634nucleusIDA10992246 
GO:0005764lysosomeIDA8895569 |11020216 
GO:0005764lysosomeISS-
GO:0005794Golgi apparatusIDA7637805 
GO:0005829cytosolISS-
GO:0008021synaptic vesicleIDASynap, Neurotransmitter (GO term level: 12)12483688 
GO:0030424axonIDAneuron, axon, Neurotransmitter (GO term level: 6)12483688 
GO:0030425dendriteIEAneuron, axon, dendrite (GO term level: 6)-
GO:0043025cell somaIEAaxon, dendrite (GO term level: 4)-
GO:0045121membrane raftIDA15929065 
 
KEGG Pathway Info
hsa00062: Fatty acid elongation in mitochondria - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 


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