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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: MASP1

Summary

GeneID

5648

Symbol

MASP1

Synonyms

Description

mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

Locus tag

Gene type

protein-coding

Map location

3q27-q28

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 2

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0003824

catalytic activity

IEA

GO:0004252

serine-type endopeptidase activity

IEA

glutamate (GO term level: 7)

GO:0004252

serine-type endopeptidase activity

TAS

glutamate (GO term level: 7)

8018603

GO:0005509

calcium ion binding

IEA

GO:0005529

sugar binding

IEA

GO:0008233

peptidase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0001867

complement activation, lectin pathway

EXP

11532276

GO:0006508

proteolysis

IEA

GO:0006958

complement activation, classical pathway

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005576

extracellular region

EXP

10639434 |10925294

GO:0043231

intracellular membrane-bounded organelle

IDA

18029348

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
C2	CO2 \| DKFZp779M0311	complement component 2	-	HPRD	10946292
C3	ARMD9 \| ASP \| CPAMD1	complement component 3	-	HPRD	9719152
FCN2	EBP-37 \| FCNL \| P35 \| ficolin-2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	-	HPRD,BioGRID	12421953
MASP2	MAP19 \| MASP-2 \| sMAP	mannan-binding lectin serine peptidase 2	Affinity Capture-Western	BioGRID	10878362
MBL2	COLEC1 \| HSMBPC \| MBL \| MBP \| MBP1 \| MGC116832 \| MGC116833	mannose-binding lectin (protein C) 2, soluble (opsonic defect)	-	HPRD,BioGRID	10878362
SERPING1	C1IN \| C1INH \| C1NH \| HAE1 \| HAE2	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	-	HPRD,BioGRID	10946292

KEGG Pathway Info

hsa04610: Complement and coagulation cascades - Homo sapiens (human)

Go to KEGG

All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	304	310	m8	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-125/351	1501	1508	1A,m8	hsa-miR-125b^brain	UCCCUGAGACCCUAACUUGUGA
miR-125/351	1501	1508	1A,m8	hsa-miR-125a^brain	UCCCUGAGACCCUUUAACCUGUG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.