Gene Page

Gene Page: PTPRA

Summary

GeneID

5786

Symbol

PTPRA

Synonyms

Description

protein tyrosine phosphatase, receptor type, A

Locus tag

RP4-534B8.1

Gene type

protein-coding

Map location

20p13

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Network

Shortest path distance of core genes in the Human protein-protein interaction network

Contribution to shortest path in PPI network: 0.0261

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0004872

receptor activity

IEA

GO:0005001

transmembrane receptor protein tyrosine phosphatase activity

TAS

2169617

GO:0016787

hydrolase activity

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006468

protein amino acid phosphorylation

IEA

GO:0006470

protein amino acid dephosphorylation

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005887

integral to plasma membrane

TAS

2169617

GO:0016020

membrane

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
FYN	MGC45350 \| SLK \| SYN	FYN oncogene related to SRC, FGR, YES	-	HPRD,BioGRID	9535845
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	An unspecified isoform of GRB2 interacts with PTPRA.	BIND	8670803
GRB2	ASH \| EGFRBP-GRB2 \| Grb3-3 \| MST084 \| MSTP084	growth factor receptor-bound protein 2	-	HPRD,BioGRID	7518772 \|8670803 \|11923305
KCNA2	HBK5 \| HK4 \| HUKIV \| KV1.2 \| MGC50217 \| MK2 \| NGK1 \| RBK2	potassium voltage-gated channel, shaker-related subfamily, member 2	Affinity Capture-Western Reconstituted Complex	BioGRID	9878055
PTPRA	HEPTP \| HLPR \| HPTPA \| HPTPalpha \| LRP \| PTPA \| PTPRL2 \| R-PTP-alpha \| RPTPA	protein tyrosine phosphatase, receptor type, A	RPTP-alpha forms a homodimer.	BIND	11401727
PTPRD	HPTP \| HPTP-DELTA \| HPTPD \| MGC119750 \| MGC119751 \| MGC119752 \| MGC119753 \| PTPD \| R-PTP-DELTA	protein tyrosine phosphatase, receptor type, D	-	HPRD	10777529
PTPRF	FLJ43335 \| FLJ45062 \| FLJ45567 \| LAR	protein tyrosine phosphatase, receptor type, F	-	HPRD	10777529
SRC	ASV \| SRC1 \| c-SRC \| p60-Src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	Affinity Capture-Western	BioGRID	11923305

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-1/206	311	317	1A	hsa-miR-1	UGGAAUGUAAAGAAGUAUGUA
				hsa-miR-206^SZ	UGGAAUGUAAGGAAGUGUGUGG
				hsa-miR-613	AGGAAUGUUCCUUCUUUGCC
miR-146	352	359	1A,m8	hsa-miR-146a	UGAGAACUGAAUUCCAUGGGUU
miR-146	352	359	1A,m8	hsa-miR-146b^brain	UGAGAACUGAAUUCCAUAGGCU
miR-218	344	351	1A,m8	hsa-miR-218^brain	UUGUGCUUGAUCUAACCAUGU
miR-495	59	65	1A	hsa-miR-495^brain	AAACAAACAUGGUGCACUUCUUU
miR-496	151	157	1A	hsa-miR-496	AUUACAUGGCCAAUCUC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.