Gene Page: C4A

Summary
GeneID  720
Symbol  C4A
Synonyms  C4|C4A2|C4A3|C4A4|C4A6|C4S|CO4|CPAMD2|MGC164979|RG
Description  complement component 4A (Rodgers blood group)
See related  HGNC:1323|MIM:120810|Ensembl:ENSG00000204319|HPRD:00401|
Locus tag  DAQB-124C11.1
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
AssociationA combined odds ratio method (Sun et al. 2008), association studies1Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004866endopeptidase inhibitor activityIEA-
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006954inflammatory responseIEA-
GO:0006956complement activationIEA-
GO:0006957complement activation, alternative pathwayEXP162484 
GO:0006958complement activation, classical pathwayIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP6019133 |12878586 |15199963 
GO:0005576extracellular regionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
APOA2-apolipoprotein A-II-HPRD7518568 
C3AR1AZ3B | C3AR | HNFAG09complement component 3a receptor 1-HPRD,BioGRID9725198 
CR1C3BR | CD35 | KNcomplement component (3b/4b) receptor 1 (Knops blood group)-HPRD,BioGRID8422437 
CST3ARMD11 | MGC117328cystatin C-HPRD,BioGRID2304899 
GPR77C5L2 | GPF77G protein-coupled receptor 77-HPRD11773063 
 
KEGG Pathway Info
hsa04610: Complement and coagulation cascades - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa05322: Systemic lupus erythematosus - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 


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