Gene Page: C5

Summary
GeneID  727
Symbol  C5
Synonyms  CPAMD4|FLJ17816|FLJ17822|MGC142298
Description  complement component 5
See related  HGNC:1331|MIM:120900|Ensembl:ENSG00000106804|HPRD:00405|
Locus tag  -
Gene type  protein-coding
Map location  9q33-q34
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004866endopeptidase inhibitor activityIEA-
GO:0005102receptor bindingTASNeurotransmitter (GO term level: 4)9590258 |10820279 
GO:0008009chemokine activityTAS10820279 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0000187activation of MAPK activityTAS7649993 
GO:0006935chemotaxisTAS10820279 
GO:0006950response to stressTAS9590258 
GO:0006954inflammatory responseIEA-
GO:0006954inflammatory responseTAS8759757 
GO:0006956complement activationIEA-
GO:0006957complement activation, alternative pathwayIEA-
GO:0006958complement activation, classical pathwayIEA-
GO:0007186G-protein coupled receptor protein signaling pathwayTAS8898085 
GO:0019835cytolysisIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP3052276 
GO:0005576extracellular regionIEA-
GO:0005579membrane attack complexIEA-
GO:0005615extracellular spaceTAS9218605 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
C2CO2 | DKFZp779M0311complement component 2-HPRD8175701 |12878586 
C3ARMD9 | ASP | CPAMD1complement component 3-HPRD,BioGRID11367533 
C5AR1C5A | C5AR | C5R1 | CD88complement component 5a receptor 1C5 (C5a) interacts with C5R1.BIND15768031 
-HPRD,BioGRID9553099 
C6-complement component 6-HPRD,BioGRID1387399 |2808363 
C7-complement component 7-HPRD,BioGRID1387399 
C8BMGC163447complement component 8, beta polypeptide-HPRD,BioGRID3624872 
CPB2CPU | PCPB | TAFIcarboxypeptidase B2 (plasma)Biochemical ActivityBioGRID11939578 
 
KEGG Pathway Info
hsa04610: Complement and coagulation cascades - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa05322: Systemic lupus erythematosus - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 


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