Gene Page: VCAM1

Summary
GeneID  7412
Symbol  VCAM1
Synonyms  CD106|DKFZp779G2333|INCAM-100|MGC99561
Description  vascular cell adhesion molecule 1
See related  HGNC:12663|MIM:192225|Ensembl:ENSG00000162692|HPRD:01888|
Locus tag  -
Gene type  protein-coding
Map location  1p32-p31
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005178integrin bindingIDA1377228 
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007157heterophilic cell adhesionIDA1715889 
GO:0022614membrane to membrane dockingIEP12082081 
GO:0030183B cell differentiationIC1715889 
GO:0042102positive regulation of T cell proliferationIDA1381355 
GO:0044419interspecies interaction between organismsIEA-
GO:0050901leukocyte tethering or rollingIEP2688898 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005615extracellular spaceIDA9290466 
GO:0005902microvillusIDA12082081 
GO:0009897external side of plasma membraneIDA1377228 
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-
GO:0030175filopodiumIDAaxon (GO term level: 5)12082081 
GO:0045177apical part of cellIDA12082081 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCL17A-152E5.3 | ABCD-2 | MGC138271 | MGC138273 | SCYA17 | TARCchemokine (C-C motif) ligand 17-HPRD,BioGRID12193695 
CCL22A-152E5.1 | ABCD-1 | DC/B-CK | MDC | MGC34554 | SCYA22 | STCP-1chemokine (C-C motif) ligand 22-HPRD,BioGRID12193695 
EZRCVIL | CVL | DKFZp762H157 | FLJ26216 | MGC1584 | VIL2ezrin-HPRD,BioGRID12082081 
IL13ALRH | BHR1 | IL-13 | MGC116786 | MGC116788 | MGC116789 | P600interleukin 13-HPRD,BioGRID7521694 
ITGADADB2 | CD11D | FLJ39841integrin, alpha D-HPRD,BioGRID10438935 
ITGB1CD29 | FNRB | GPIIA | MDF2 | MSK12 | VLA-BETA | VLABintegrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)-HPRD12097820 
ITGB7-integrin, beta 7-HPRD12682249 
MSN-moesin-HPRD,BioGRID12082081 
-HPRD7884872|12082081 
SEC61B-Sec61 beta subunitVCAM1 interacts with SEC61B. This interaction was modeled on a demonstrated interaction between human VCAM1 and canine SEC61B.BIND16015337 
 
KEGG Pathway Info
hsa04514: Cell adhesion molecules (CAMs) - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa04670: Leukocyte transendothelial migration - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-4962632691Ahsa-miR-496AUUACAUGGCCAAUCUC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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