Gene Page: CAD

Summary
GeneID  790
Symbol  CAD
Synonyms  -
Description  carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
See related  HGNC:1424|MIM:114010|Ensembl:ENSG00000084774|HPRD:06437|
Locus tag  -
Gene type  protein-coding
Map location  2p22-p21
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.0139 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004070aspartate carbamoyltransferase activityIEA-
GO:0004086carbamoyl-phosphate synthase activityIEA-
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activityTASglutamate (GO term level: 6)8619816 
GO:0004151dihydroorotase activityEXP8619816 
GO:0004151dihydroorotase activityIEA-
GO:0005524ATP bindingIEA-
GO:0008270zinc ion bindingIEA-
GO:0016597amino acid bindingIEA-
GO:0016740transferase activityIEA-
GO:0016874ligase activityIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006207'de novo' pyrimidine base biosynthetic processIEA-
GO:0006221pyrimidine nucleotide biosynthetic processIEA-
GO:0006520amino acid metabolic processIEA-
GO:0006541glutamine metabolic processIEA-
GO:0006807nitrogen compound metabolic processIEA-
GO:0009058biosynthetic processIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIEA-
GO:0005829cytosolEXP8619816 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
MAP3K7TAK1 | TGF1amitogen-activated protein kinase kinase kinase 7-HPRD14743216 
MAP3K7IP2FLJ21885 | KIAA0733 | TAB2mitogen-activated protein kinase kinase kinase 7 interacting protein 2-HPRD14743216 
TRADDHs.89862 | MGC11078TNFRSF1A-associated via death domain-HPRD14743216 
 
KEGG Pathway Info
hsa00240: Pyrimidine metabolism - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa00251: Glutamate metabolism - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa00252: Alanine and aspartate metabolism - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 


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