Gene Page: CD2

Summary
GeneID  914
Symbol  CD2
Synonyms  SRBC|T11
Description  CD2 molecule
See related  HGNC:1639|MIM:186990|Ensembl:ENSG00000116824|HPRD:01750|
Locus tag  RP4-655N15.2
Gene type  protein-coding
Map location  1p13
 
Gene in Data Sources
Gene set nameMethod of gene setEvidenceInfo
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
Gene Expression ?
 
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityNAS7544493 
GO:0005515protein bindingIPI1970422 |7544493 |12356317 
GO:0005515protein bindingISS7544493 |12356317 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001766membrane raft polarizationTAS11376005 |11591762 
GO:0006917induction of apoptosisTAS9270771 |10575274 
GO:0007166cell surface receptor linked signal transductionTAS10575274 
GO:0016337cell-cell adhesionNAS7544493 
GO:0030101natural killer cell activationNAS12714509 
GO:0030887positive regulation of myeloid dendritic cell activationNASdendrite (GO term level: 9)12714509 
GO:0042110T cell activationTAS2471997 
GO:0045580regulation of T cell differentiationNAS11544295 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005887integral to plasma membraneNAS7544493 
GO:0009897external side of plasma membraneIEA-
GO:0016020membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD247CD3-ZETA | CD3H | CD3Q | CD3Z | T3Z | TCRZCD247 molecule-HPRD8977276 
CD2APCMS | DKFZp586H0519CD2-associated proteinReconstituted ComplexBioGRID12690097 
-HPRD9741631 
CD2BP2FWP010 | LIN1 | Snu40 | U5-52KCD2 (cytoplasmic tail) binding protein 2-HPRD,BioGRID9843987 
CD4CD4mutCD4 molecule-HPRD7539755 
CD48BCM1 | BLAST | BLAST1 | MEM-102 | SLAMF2 | hCD48 | mCD48CD48 molecule-HPRD,BioGRID12356317 
CD5LEU1 | T1CD5 molecule-HPRD,BioGRID10510361 
CD53MOX44 | TSPAN25CD53 molecule-HPRD,BioGRID1346273 
CD58LFA-3 | LFA3CD58 molecule-HPRD,BioGRID1377404 |11575926 
CD5916.3A5 | 1F5 | EJ16 | EJ30 | EL32 | FLJ38134 | FLJ92039 | G344 | HRF-20 | HRF20 | MAC-IP | MACIF | MEM43 | MGC2354 | MIC11 | MIN1 | MIN2 | MIN3 | MIRL | MSK21 | p18-20CD59 molecule, complement regulatory protein-HPRD1377404 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID9677430 
ITKEMT | LYK | MGC126257 | MGC126258 | PSCTK2IL2-inducible T-cell kinaseAffinity Capture-WesternBioGRID9677430 
LCKYT16 | p56lck | pp58lcklymphocyte-specific protein tyrosine kinase-HPRD,BioGRID8551220 
LGALS1DKFZp686E23103 | GAL1 | GBPlectin, galactoside-binding, soluble, 1-HPRD,BioGRID10642604 
MXD1MAD | MAD1 | MGC104659MAX dimerization protein 1-HPRD,BioGRID11602341 
PSTPIP1CD2BP1 | CD2BP1L | CD2BP1S | H-PIP | PAPAS | PSTPIPproline-serine-threonine phosphatase interacting protein 1-HPRD,BioGRID9857189 
PTPRCB220 | CD45 | CD45R | GP180 | LCA | LY5 | T200protein tyrosine phosphatase, receptor type, C-HPRD,BioGRID1970422 |1976695 
SH3KBP1CIN85 | GIG10 | MIG18SH3-domain kinase binding protein 1-HPRD12690097 
-HPRD,BioGRID9857189 |12690097|12690097 
SETA interacts with CD2. This interaction was modelled on a demonstrated interaction between rat SETA and human CD2.BIND11152963 
SP1-Sp1 transcription factor-HPRD7933095 
 
KEGG Pathway Info
hsa04514: Cell adhesion molecules (CAMs) - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
hsa04640: Hematopoietic cell lineage - Homo sapiens (human)Go to KEGGAll SZGR genes in this pathway
 


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