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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: MAGI1

Summary

GeneID

9223

Symbol

MAGI1

Synonyms

AIP3|BAIAP1|BAP1|MAGI-1|TNRC19|WWP3

Description

membrane associated guanylate kinase, WW and PDZ domain containing 1

Locus tag

Gene type

protein-coding

Map location

3p14.1

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

Association

A combined odds ratio method (Sun et al. 2008), association studies

Link to SZGene

Literature

High-throughput literature-search

Co-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]

Click to show detail

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0000166

nucleotide binding

IEA

GO:0005524

ATP binding

IEA

GO:0008022

protein C-terminus binding

TAS

9647739

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006461

protein complex assembly

NAS

9647739

GO:0007155

cell adhesion

TAS

9647739

GO:0007166

cell surface receptor linked signal transduction

TAS

9647739

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005886

plasma membrane

TAS

9647739

GO:0005923

tight junction

IEA

Brain (GO term level: 10)

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ACCN3	ASIC3 \| DRASIC \| SLNAC1 \| TNaC1	amiloride-sensitive cation channel 3	-	HPRD,BioGRID	15317815
ACCN3	ASIC3 \| DRASIC \| SLNAC1 \| TNaC1	amiloride-sensitive cation channel 3	ASIC3 interacts with MAGI-1B.	BIND	15317815
ACTN4	ACTININ-4 \| DKFZp686K23158 \| FSGS \| FSGS1	actinin, alpha 4	-	HPRD,BioGRID	12042308
ATN1	B37 \| D12S755E \| DRPLA \| NOD	atrophin 1	Atrophin-1 interacts with AIP-3.	BIND	9647693
ATN1	B37 \| D12S755E \| DRPLA \| NOD	atrophin 1	-	HPRD,BioGRID	9647693
BAI1	FLJ41988	brain-specific angiogenesis inhibitor 1	-	HPRD,BioGRID	9647739
BZW1	BZAP45 \| KIAA0005 \| Nbla10236	basic leucine zipper and W2 domains 1	Affinity Capture-MS	BioGRID	17353931
CDH1	Arc-1 \| CD324 \| CDHE \| ECAD \| LCAM \| UVO	cadherin 1, type 1, E-cadherin (epithelial)	Affinity Capture-Western	BioGRID	10772923
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	10772923
DLL1	DELTA1 \| DL1 \| Delta	delta-like 1 (Drosophila)	Delta1 interacts with MAGI-1.	BIND	15509766
FCHSD2	KIAA0769 \| NWK \| SH3MD3	FCH and double SH3 domains 2	Affinity Capture-Western Reconstituted Complex Two-hybrid	BioGRID	14627983
IL6R	CD126 \| IL-6R-1 \| IL-6R-alpha \| IL6RA \| MGC104991	interleukin 6 receptor	-	HPRD	9169421
LRP2	DBS \| gp330	low density lipoprotein-related protein 2	-	HPRD,BioGRID	11274227
NET1	ARHGEF8 \| NET1A	neuroepithelial cell transforming 1	-	HPRD,BioGRID	11350080
RASA1	CM-AVM \| CMAVM \| DKFZp434N071 \| GAP \| PKWS \| RASA \| RASGAP \| p120GAP \| p120RASGAP	RAS p21 protein activator (GTPase activating protein) 1	-	HPRD	9169421
SFN	YWHAS	stratifin	Affinity Capture-MS	BioGRID	15778465
SYNPO	KIAA1029	synaptopodin	-	HPRD,BioGRID	12042308
TP53BP2	53BP2 \| ASPP2 \| BBP \| PPP1R13A \| p53BP2	tumor protein p53 binding protein, 2	-	HPRD	9169421
WBP1	MGC15305 \| WBP-1	WW domain binding protein 1	Protein-peptide	BioGRID	9169421
WBP2	MGC18269 \| WBP-2	WW domain binding protein 2	Protein-peptide	BioGRID	9169421

KEGG Pathway Info

hsa04530: Tight junction - Homo sapiens (human)	Go to KEGG	All SZGR genes in this pathway
hsa05050: Dentatorubropallidoluysian atrophy (DRPLA) - Homo sapiens (human)	Go to KEGG	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-101	1455	1462	1A,m8	hsa-miR-101	UACAGUACUGUGAUAACUGAAG
miR-153	1929	1935	m8	hsa-miR-153	UUGCAUAGUCACAAAAGUGA
miR-182	237	244	1A,m8	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-185	328	334	m8	hsa-miR-185^brain	UGGAGAGAAAGGCAGUUC
miR-188	255	262	1A,m8	hsa-miR-188	CAUCCCUUGCAUGGUGGAGGGU
miR-205	576	583	1A,m8	hsa-miR-205	UCCUUCAUUCCACCGGAGUCUG
miR-23	1628	1634	m8	hsa-miR-23a^brain	AUCACAUUGCCAGGGAUUUCC
miR-23	1628	1634	m8	hsa-miR-23b^brain	AUCACAUUGCCAGGGAUUACC
miR-24	1315	1322	1A,m8	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG
miR-320	1959	1965	1A	hsa-miR-320	AAAAGCUGGGUUGAGAGGGCGAA
miR-323	1628	1634	1A	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
miR-34b	1306	1313	1A,m8	hsa-miR-34b	UAGGCAGUGUCAUUAGCUGAUUG
miR-381	1587	1594	1A,m8	hsa-miR-381	UAUACAAGGGCAAGCUCUCUGU
miR-411	26	32	m8	hsa-miR-411	AACACGGUCCACUAACCCUCAGU
miR-496	1707	1713	1A	hsa-miR-496	AUUACAUGGCCAAUCUC
miR-96	238	244	1A	hsa-miR-96^brain	UUUGGCACUAGCACAUUUUUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.