Gene Page

Gene Page: SLC4A7

Summary

GeneID

9497

Symbol

SLC4A7

Synonyms

DKFZp686H168|NBC2|NBC3|SBC2|SLC4A6

Description

solute carrier family 4, sodium bicarbonate cotransporter, member 7

Locus tag

Gene type

protein-coding

Map location

3p22

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.006

GO_Annotation

Mapping neuro-related keywords to Gene Ontology annotations

Hits with neuro-related keywords: 1

Gene Expression ?

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005215

transporter activity

IEA

GO:0005452

inorganic anion exchanger activity

IEA

GO:0005515

protein binding

IPI

17353931

GO:0008509

anion transmembrane transporter activity

IEA

GO:0008510

sodium:bicarbonate symporter activity

NAS

10347222

GO:0015293

symporter activity

IEA

GO:0031402

sodium ion binding

IEA

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0006814

sodium ion transport

IEA

GO:0006820

anion transport

IEA

GO:0015701

bicarbonate transport

NAS

10347222

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005886

plasma membrane

IEA

GO:0016021

integral to membrane

NAS

10347222

GO:0016323

basolateral plasma membrane

IEA

GO:0016324

apical plasma membrane

IEA

GO:0042995

cell projection

IEA

axon (GO term level: 4)

Interactions

Shown by Network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CFTR	ABC35 \| ABCC7 \| CF \| CFTR/MRP \| MRP7 \| TNR-CFTR \| dJ760C5.1	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	-	HPRD,BioGRID	12403779
SLC4A4	DKFZp781H1314 \| HNBC1 \| KNBC \| NBC1 \| NBC2 \| SLC4A5 \| hhNMC \| pNBC	solute carrier family 4, sodium bicarbonate cotransporter, member 4	-	HPRD	10600945
YWHAB	GW128 \| HS1 \| KCIP-1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	Affinity Capture-MS	BioGRID	17353931

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
let-7/98	2417	2423	1A	hsa-let-7a^brain	UGAGGUAGUAGGUUGUAUAGUU
				hsa-let-7b^brain	UGAGGUAGUAGGUUGUGUGGUU
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	UGAGGUAGUAGUUUGUGCUGU
miR-124.1	2369	2376	1A,m8	hsa-miR-124a	UUAAGGCACGCGGUGAAUGCCA
miR-124/506	2369	2375	1A	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	2369	2375	1A	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-137	4019	4025	1A	hsa-miR-137	UAUUGCUUAAGAAUACGCGUAG
miR-15/16/195/424/497	1908	1915	1A,m8	hsa-miR-15a^brain	UAGCAGCACAUAAUGGUUUGUG
				hsa-miR-16^brain	UAGCAGCACGUAAAUAUUGGCG
				hsa-miR-15b^brain	UAGCAGCACAUCAUGGUUUACA
				hsa-miR-195^SZ	UAGCAGCACAGAAAUAUUGGC
				hsa-miR-424	CAGCAGCAAUUCAUGUUUUGAA
				hsa-miR-497	CAGCAGCACACUGUGGUUUGU
miR-17-5p/20/93.mr/106/519.d	2479	2485	m8	hsa-miR-17-5p	CAAAGUGCUUACAGUGCAGGUAGU
				hsa-miR-20a^brain	UAAAGUGCUUAUAGUGCAGGUAG
				hsa-miR-106a	AAAAGUGCUUACAGUGCAGGUAGC
				hsa-miR-106b^SZ	UAAAGUGCUGACAGUGCAGAU
				hsa-miR-20b^SZ	CAAAGUGCUCAUAGUGCAGGUAG
				hsa-miR-519d	CAAAGUGCCUCCCUUUAGAGUGU
miR-182	2876	2882	m8	hsa-miR-182	UUUGGCAAUGGUAGAACUCACA
miR-183	1199	1205	1A	hsa-miR-183	UAUGGCACUGGUAGAAUUCACUG
miR-26	2183	2189	m8	hsa-miR-26a^brain	UUCAAGUAAUCCAGGAUAGGC
miR-26	2183	2189	m8	hsa-miR-26b^SZ	UUCAAGUAAUUCAGGAUAGGUU
miR-30-5p	2597	2604	1A,m8	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA
miR-34/449	1196	1203	1A,m8	hsa-miR-34a^brain	UGGCAGUGUCUUAGCUGGUUGUU
				hsa-miR-34c	AGGCAGUGUAGUUAGCUGAUUGC
				hsa-miR-449	UGGCAGUGUAUUGUUAGCUGGU
				hsa-miR-449b	AGGCAGUGUAUUGUUAGCUGGC
miR-363	2426	2432	1A	hsa-miR-363	AUUGCACGGUAUCCAUCUGUAA
miR-410	3768	3774	1A	hsa-miR-410	AAUAUAACACAGAUGGCCUGU
miR-486	2008	2014	1A	hsa-miR-486	UCCUGUACUGAGCUGCCCCGAG
miR-500	2424	2431	1A,m8	hsa-miR-500	AUGCACCUGGGCAAGGAUUCUG
miR-503	1909	1915	1A	hsa-miR-503	UAGCAGCGGGAACAGUUCUGCAG

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.